What is Atrophoderma of Pasini and Pierini?
Atrophoderma of Pasini and Pierini (APP) is a rare skin disorder affecting dermal collagen and presenting with dermal atrophy. The classic clinical manifestations of APP are hyperpigmented or hypopigmented, depressed areas of skin on the trunk or extremities (picture 1).
What does Atrophoderma mean?
Atrophoderma refers to conditions involving skin atrophy. Types include: Follicular atrophoderma. Linear atrophoderma of Moulin.
Can Atrophoderma be cured?
There is no recognised treatment for atrophoderma of Pasini and Pierini. Cases associated with B burgdorferi antibodies may improve with doxycycline. Hydroxychloroquine and methotrexate have been reported to be co-incidentally effective in rare cases with associated disorders such as lupus erythematosus or psoriasis.
What is Pierini?
Atrophoderma of Pasini and Pierini (ATPP) is a rare skin condition that results in patchy areas of discolored skin. The main symptom of Atrophoderma of Pasini and Pierini is multiple irregularly shaped, dark or light areas of skin in which the tissue under the skin breaks down resulting in a depression (dent).
What causes Morphea scleroderma?
What causes morphea scleroderma? While the exact cause of morphea is unknown, potential contributing factors include an atypical reaction of the immune system, recent infection, repeated skin trauma, exposure to chemical toxins, or exposure to radiation.
What is Morphea diagnosis?
Morphea is a rare skin condition characterized by small red or purple patches that develop firm white or ivory centers. The affected skin becomes tight and less flexible. Morphea (mor-FEE-uh) is a rare condition that causes painless, discolored patches on your skin.
What is morphea diagnosis?
What can trigger morphea?
Morphea may be triggered by radiation therapy, repeated trauma to your skin, environmental exposure, or an infection. Morphea isn’t contagious, so you can’t get it from or spread it by touching someone else.
How do you stop the spread of morphea?
For severe or widespread morphea, your doctor may prescribe an immunosuppressive medication, such as oral methotrexate (Trexall), corticosteroid pills or both. Or your doctor may suggest hydroxychloroquine (Plaquenil) or mycophenolate mofetil. Each of these drugs has potential side effects.
How does morphea start?
The cause of morphea is unknown. It may be caused by an unusual reaction of your immune system. In people at increased risk of morphea, it could be triggered by injury to the affected area, medications, chemical toxins, an infection or radiation therapy. The condition isn’t contagious.
What kind of doctor treats morphea?
You may start by seeing your primary care doctor. He or she may refer you to a doctor who specializes in skin disorders (dermatologist) or a specialist in diseases of the joints, bones and muscles (rheumatologist).
What are the side effects of morphea?
Complications
- Self-esteem issues. Morphea can have a negative effect on your self-esteem and body image, particularly if discolored patches of skin appear on your arms, legs or face.
- Movement problems.
- Widespread areas of hardened, discolored skin.
- Loss of hair and sweat glands.
- Eye damage.