Is Lipitor better than lovastatin?
Atorvastatin is generally considered a more potent drug than lovastatin for lowering LDL-cholesterol levels. However, atorvastatin may carry a higher risk of myopathy in higher doses compared to lovastatin.
Which statin is the best choice for which patient?
Statins lower cholesterol levels through inhibition of HMG-CoA reductase. The synthetic and natural statins have essentially equivalent efficacy at improving the lipid profile. However, in patients who do not achieve their LDL goals, atorvastatin and simvastatin may be the best choices for initial therapy.
What is the safest most effective statin drug?
Results. Rosuvastatin (10 mg) was the most effective at reducing LDL-C (29.03%). Atorvastatin reduced LDL-C the most at a dose of 40 mg (22.8%), and pravastatin reduced LDL-C the most at a dose of 20 mg (20.3%). All three statins were safe in relation to muscular and hepatic functions.
Is there a better statin than Lipitor?
The study concluded that Crestor lowered LDL cholesterol by 8.2% more than Lipitor, and Crestor lowered total cholesterol significantly more than all the other statins studied. Crestor also increased HDL cholesterol (the good kind of cholesterol) more than Lipitor did.
Who should not take lovastatin?
It should not be used in children younger than 18 years. The liver and kidneys of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time.
What are the negative effects of lovastatin?
Call your doctor right away if you have a headache, stomach pain, vomiting, dark urine, loss of appetite, weight loss, general feeling of tiredness or weakness, light-colored stools, upper right stomach pain, or yellow eyes or skin.
Which statin has least side effects?
According to a research review people who take simvastatin (Zocor) or pravastatin (Pravachol) may experience fewer side effects.
Which statin is easiest on liver?
Low dose statins like atorvastatin (Lipitor) are safe in patients with mild liver disease (for example, patients with fatty liver and mildly abnormal liver tests in the blood such as ALT and AST).
What is the best statin to take with least side effects?
What is the best statin to take with the least side effects?
What is the most serious side effect of lovastatin?
Important warnings. Serious muscle damage warning: Using lovastatin raises your risk of serious muscle problems. These problems include myopathy, with symptoms that include muscle pain, tenderness, or weakness. Myopathy can lead to rhabdomyolysis.
Can you just stop taking lovastatin?
Do not suddenly stop taking your prescribed medication without talking with your doctor first. If you have side effects from the medication, your doctor might adjust your dosage or recommend a different statin or other combination of medications.
Is liver damage from statins reversible?
Fortunately, severe liver injury is uncommon with statin use and is generally reversible without any intervention other than offending statin cessation.
Which statin has least muscle side effects?
Is muscle pain a side effect of all statins? Even though all statins are similar chemically, they have some minor differences that could impact how likely they are to cause muscle pain. Simvastatin is the most likely to cause muscle pain, and fluvastatin is the least likely.
Which statin has the least amount of side effects?
Why do statins have to be taken at night?
Many statins work more effectively when they are taken at night. This is because the enzyme which makes the cholesterol is more active at night. Also, the half-life, or the amount of time it takes for half the dose to leave your body, of some statins is short.
Do most cardiologists take statins?
What a Cardiologist Wants You to Know. About 35 million people take statins in the United States, but research says only 55% of those who are recommended to take a statin are taking one.
Why do statins make your legs ache?
The researchers suggest that in most people, muscle cells can tolerate this calcium leak. However, in people already susceptible due to their genes or lifestyle, the leak caused by statins may overwhelm the muscle cells, giving rise to muscle pain and weakness.
Which statin is least likely to cause leg pain?
Can I drink coffee while taking statin?
Caffeine is a nonspecific adenosine receptor blocker, and thus drinking CC may block the myocardial protective effects of statins.
Can you get off statins Once you start?
It’s possible for some people to stop taking statins safely, but it can be especially risky for others. For instance, if you have a history of heart attack or stroke, it’s not recommended that you stop taking these drugs. This is because you’re more likely to have another such problem when you discontinue statins.
Do statins raise a1c?
Changes in HbA1c in new users of high-potency statins
Compared with the baseline value, the use of high-potency statins significantly increased HbA1c levels in patients both with and without diabetes. The effect on HbA1c levels was significantly higher in patients with diabetes compared to those without (p = 0.02).
Which statin has least muscle pain?
What to avoid while taking a statin?
A: While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.
Which statin raises blood sugar the most?
More potent statins like atorvastatin, rosuvastatin and simvastatin cause a larger increase in blood sugar than less potent statins like pravastatin.