Is docetaxel a strong chemo?
Because the active ingredient, docetaxel, is a strong chemotherapy drug, it also has a long list of side effects. Most of them are typical for drugs in this class, such as nausea, vomiting and temporary alopecia (hair loss).
How long is docetaxel treatment?
You usually have a course of several cycles of treatment over a few months. Each cycle of docetaxel usually takes 21 days (3 weeks). You have docetaxel on the first day of each cycle. Your nurse or doctor will discuss your treatment plan with you.
What cancers does docetaxel treat?
What Docetaxel Is Used For: Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer. Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma.
What is the most common side effect of docetaxel?
Two of the most common long-term side effects of docetaxel chemotherapy are sensory and motor peripheral neuropathy. Fortunately, the incidence of both of these is much less than paclitaxel. Grade 3 and 4 neuropathy is only observed in less than 10% of patients receiving docetaxel therapy.
What is the success rate of docetaxel?
This initial study led by Rosenthal and colleagues found that docetaxel improved OS from 89% to 93% (hazard ratio (HR); 0.69; 90% CI, 0.49 to 0.97; one-sided P = . 034).
How many cycles of docetaxel can you have?
In a clinical trial of docetaxel for CRPC, the frequencies of PN were 32% [1] (maximum 10 cycles) and 41% (maximum 12 cycles) [17]. Considering the results of the present study, the incidence of PN with docetaxel is higher in patients with CRPC than in those with other cancers.
How many times can you have docetaxel?
Docetaxel is normally given once every three weeks, over about one hour.
What is the survival rate of docetaxel?
Overall survival rates at 4 years were 89% in the standard treatment arm and 93% in the standard treatment plus docetaxel-based chemotherapy arm. Six-year rates for disease-free survival were 55% in the standard treatment arm and 65% in the standard treatment plus docetaxel arm.
How do you feel after docetaxel?
Docetaxel may cause severe lack or loss of strength, which can last a few days up to several weeks. Tell your doctor if you unusual tiredness or weakness. This medicine contains alcohol and may cause some people to become drowsy, dizzy, or less alert than they are normally.
How long can you live with docetaxel?
The median overall survival (OS) was 81 months with docetaxel plus standard of care (hormonal therapy with or without radiotherapy) versus 71 months with standard of care alone (0.78; 95% CI, 0.66-0ยท93;P= . 006).