What is H.P. Acthar Gel used for?
Acthar® Gel is a prescription medicine used for: Treatment for flares or on a regular basis (maintenance) in people with dermatomyositis or polymyositis (DM-PM) Treatment for flares or on a regular basis (maintenance) in people with systemic lupus erythematosus (lupus)
How is acthar dosed?
The usual dose of Acthar Gel is 40-80 units given intramuscularly or subcutaneously every 24-72 hours. Although drug dependence does not occur, sudden withdrawal of Acthar Gel after prolonged use may lead to adrenal insufficiency or recurrent symptoms which make it difficult to stop the treatment.
How often do you take acthar Gel?
Acthar Gel injections are usually given once daily for two to three weeks to treat a severe exacerbation, although the dose and frequency should be determined specifically for each patient by the treating physician. Once injected, Acthar Gel is absorbed slowly into the bloodstream.
How long does it take Acthar Gel to work?
The new ACTRIMS data suggest that it can lead to “significant improvements after two months of use” for those who experience stubborn flares that fail to respond to high-dose corticosteroid treatments. These improvements were shown to last for at least six months.
How do you inject acthar Gel?
Take the vial of Acthar out of the refrigerator. Always inject Acthar into the muscle of your child. Never inject Acthar directly into a vein, under your child’s skin, or give it to your child by mouth. Keep needle tip in the Acthar at all times when drawing the amount your doctor prescribed.
What drug class is acthar Gel?
H.P. Acthar Gel is a prescription medicine used to treat the symptoms of Nephrotic Syndrome, Acute Exacerbations of Multiple Sclerosis and Verification of Adrenal Responsiveness. H.P. Acthar Gel may be used alone or with other medications. H.P. Acthar Gel belongs to a class of drugs called Corticosteroids.
What are the side effects of Acthar Gel?
Side effects of H.P. Acthar Gel include:
- infections,
- stomach ulcers, and.
- changes in mood and behavior such as irritability or depression,
- trouble sleeping,
- acne,
- dry skin,
- thinning skin,
- bruising or discoloration,
Is acthar FDA approved?
Acthar Gel is FDA-Approved for 19 Indications Acthar Gel is often prescribed by doctors predominately as a later-line treatment to a small subset of patients suffering from various, sometimes devastating, diseases and may be the last treatment option for those who need an alternative therapy.
Is Acthar Gel generic?
There is no generic version of H.P. Acthar Gel, a prescription drug that is given by injection to treat multiple sclerosis, infantile spasms, some types of arthritis and several other medical conditions. H.P. Acthar Gel is sometimes referred to as ACTH, corticotropin or repository corticotropin.
Is Acthar Gel still available?
Acthar Gel (corticotropin) is an injectable medication used to treat seizures in infants, multiple sclerosis, rheumatoid arthritis, and other conditions. For most conditions, it needs to be injected every day for a few weeks. It’s currently only available as a brand-name medication, so it might be expensive.
Is Acthar Gel FDA approved?
Acthar Gel is FDA-Approved for 19 Indications Acthar Gel has an established efficacy and safety profile as well as a long track record of clinical evidence that spans nearly 70 years. In addition, Acthar Gel has 19 indications, including infantile spasms which was approved in 2010.
What is HPP Acthar gel?
H.P. Acthar Gel 1 DESCRIPTION. H.P. Acthar Gel is a highly purified sterile preparation of… 2 INDICATIONS. H.P. Acthar Gel (repository corticotropin injection) is indicated as monotherapy… 3 DOSAGE AND ADMINISTRATION. In the treatment of infantile spasms, H.P. 4 HOW SUPPLIED. 5 mL multi-dose vial containing 80 USP Units per mL…
How many units are in an Acthar gel?
*Acthar Gel is provided as a 5-mL multidose vial containing 80 USP units per mL. † It may be necessary to taper the dose. ‡ Dosing should then be gradually tapered over a 2-week period to avoid adrenal insufficiency. No-cost, one-on-one injection training is available for your patients.
How do you store Acthar gel vials?
Store vials of Acthar Gel in the refrigerator between 36°F to 46°F (2°C to 8°C). Throw away any vials after the expiration date printed on the label. Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. Do not use Acthar Gel for a condition for which it has not been prescribed.
What is Acthar gel for MS?
What is Acthar Gel? Treatment for adults with acute relapses or flares of multiple sclerosis (MS). Studies have shown Acthar to be effective in speeding recovery from an MS relapse. However, there is no evidence that it affects the ultimate outcome or natural history of the disease What is Acthar Gel?