What are MIA PaCa 2 cells?
MIA PaCa-2 is an epithelial cell line that was derived from tumor tissue of the pancreas obtained from a 65-year-old, White male. This cell line can be used in cancer research. Discounts may be available for our fellow nonprofit organizations.
What is PANC 1 cell line?
PANC-1 is a cell line exhibiting epithelial morphology that was isolated from the pancreatic duct of a 56-year-old, White, male with epithelioid carcinoma. This cell line can be used in cancer research. Powered by Bioz See more details on Bioz. Homo sapiens, human. Morphology epithelial Tissue Pancreas; Duct Disease.
Where do cancers most often occur in the pancreas?
Most pancreatic cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic adenocarcinoma or pancreatic exocrine cancer. Less frequently, cancer can form in the hormone-producing cells or the neuroendocrine cells of the pancreas.
What are HT 29 cells?
Description. HT-29 is a human colorectal adenocarcinoma cell line with epithelial morphology. These cells are sensitive to the chemotherapeutic drugs 5-fluorouracil and oxaliplatin, which are standard treatment options for colorectal cancer.
What is HCT116 cell line?
HCT116 (ATCC® CCL-247™) is a human colorectal carcinoma cell line initiated from an adult male. The cells are adherent with an epithelial morphology. Following implantation into immunocompromised mice, the cells form primary tumors and distant metastases.
What is A549 cell line?
A549 cells are lung carcinoma epithelial cells that constitute a cell line. A549 is one of the commonly used cell lines for a wide range of research applications. In this article, we will provide you with all the information you will need to work with these cells.
Where do AsPC-1 pancreatic adenocarcinoma cells come from?
AsPC-1 cells originated from pancreas ascites from an adenocarcinoma patient. These cells also have the epithelial cell like morphology but are moderately to highly differentiated with the doubling time of about 58 hours.
What are AsPC-1 pancreatic adenocarcinoma cells?
AsPC-1 is cell line derived from nude mouse xenografts initiated with cells from the ascites of a 62-year-old, White, female patient with cancer of the pancreas. This cell line can be used in cancer research.
Is it better to have tumor in head or tail of pancreas?
In conclusion, our study confirms that primary tumor location in the head of the pancreas at the time of diagnosis is a significant predictor of better survival.
How long can you live with a tumor on your pancreas?
The average patient diagnosed with late-stage pancreatic cancer will live for about 1 year after diagnosis.
What are HuH 7 cells?
HuH-7 (hereafter Huh7) is a permanent cell line established from male hepatoma tissue, which was surgically removed from a 57-year-old Japanese male in 1982 (Nakabayashi et al., 1982). Huh7 and its derivatives have been used as a convenient experimental substitute for primary hepatocytes.
What is K562 cell line?
Cell Line Description
K562 cells were established the first human immortalized myelogenous leukemia line. This cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. They can be used as a highly sensitive target for the in vitro natural killer assay.
What mutations do A549 cells have?
The A549 cell line is in turn wild-type against other common mutations in lung cancer such as, EGFR, PIK3CA, TP53, ALK and PTEN. The SW900 cell line is also wild-type for these mutations with the exception for the inactivated mutation in the tumor suppressor gene TP53 (homozygous, c.
Why do we use A549 cells?
The A549 cells have been used to model the alveolar Type II pulmonary epithelium. Studies have shown that this can be particularly useful in research for studying the metabolic processing of lung tissue and for identifying mechanisms of drug delivery to the tissue.
What are AsPC 1 pancreatic adenocarcinoma cells?
What is PC3 cell line?
PC3 (PC-3) is a human prostate cancer cell line used in prostate cancer research and drug development. PC3 cells are useful in investigating biochemical changes in advanced prostate cancer cells and in assessing their response to chemotherapeutic agents.
Where do AsPC 1 pancreatic adenocarcinoma cells come from?
Can you live without the tail of your pancreas?
It’s possible to live without a pancreas. But when the entire pancreas is removed, people are left without the cells that make insulin and other hormones that help maintain safe blood sugar levels.
Can you remove a tumor in the tail of the pancreas?
Removing the tail of the pancreas (distal pancreatectomy)
Many people have cancer that has spread and so it can’t be completely removed. . You might need to have medicines for diabetes, such as insulin, after this type of surgery. And you may need to take enzymes to help with digestion.
How serious is a tumor on the pancreas?
Compared to other cancers, pancreatic cancer is relatively rare. But it is the third leading cause of cancer death in the United States. Only about 8.5% of patients with pancreatic cancer are alive five years after their diagnosis. This one of the lowest survival rates for any kind of cancer.
How fast do pancreatic tumors grow?
After the first cancer cell appears, it takes an average of nearly seven years for that cell to turn into the billions that make up a cancerous tumor the size of a plum, after which at least one of the cells within the tumor has the potential and ability to spread to other organs.
What is the difference between HepG2 and Huh-7?
In this way, HepG2 cells carry wild-type p53, whereas Hep3B and Huh7 cells have null and point mutations at p53 codon 220 respectively. Hep G2 cells mostly used for research to find level of cytotoxicity and cellular metabolism and drug metabolism in the induced cell line.
What are immortal cells?
Immortalized cell lines are cells that have been manipulated to proliferate indefinitely and can thus be cultured for long periods of time (Table 13.1). Immortalized cell lines are derived from a variety of sources that have chromosomal abnormalities or mutations that permit them to continually divide, such as tumors.
Is K562 an AML cell line?
K562, HL-60 and THP1 are used as cell models for researching CML and AML.
Why are K562 cells used?
K562 cells were established the first human immortalized myelogenous leukemia line. This cell line is derived from a 53-year-old female chronic myelogenous leukemia patient in blast crisis. They can be used as a highly sensitive target for the in vitro natural killer assay.