What are the long-term effects of omphalocele?
Long-term care. Children with conditions like giant omphalocele can face a variety of complications as they grow, including a secondary condition called pulmonary hypoplasia that may result in problems with breathing, feeding, heart function, hearing and other developmental milestones.
Why does omphalocele have a poor prognosis?
Obstetric Ultrasound
Omphalocele has a worse prognosis because it is associated with a significantly increased incidence of chromosomal abnormalities (approximately 12%).
What is the prognosis of omphalocele?
Most babies with omphaloceles do well. The survival rate is over 90 percent if the baby’s only issue is an omphalocele. The survival rate for babies who have an omphalocele and serious problems with other organs is about 70 percent.
What is omphalocele associated with?
Clinical and epidemiologic notes. Omphalocele is frequently (50% of cases or more) associated with other findings: With other unrelated birth defects, particularly cardiac, urogenital, brain, spina bifida. With certain complex anomaly patterns (OEIS [omphalocele, cloacal exstrophy, imperforate anus, spinal defects]).
What is considered a giant omphalocele?
A giant omphalocele is a liver-containing protrusion through an abdominal defect wider than 5 cm in diameter. The giant form with a small abdominal wall defect is a rare condition which, to our knowledge, has not been described previously.
Is omphalocele life threatening?
Omphalocele is a life-threatening condition. It needs to be treated soon after birth so that the baby’s organs can develop and be protected in the belly.
Which is the most prevalent abnormality diagnosed with omphalocele?
The most common syndrome is the Beckwith-Wiedemann syndrome (BWS), seen in 3 to 22% of omphaloceles [4, 22, 27].
Is omphalocele inherited?
When an abdominal wall defect, most often omphalocele, is a feature of a genetic condition, it is inherited in the pattern of that condition.
What is a characteristic of an omphalocele?
Omphalocele (pronounced uhm-fa-lo-seal) is a birth defect of the abdominal (belly) wall. The infant’s intestines, liver, or other organs stick outside of the belly through the belly button. The organs are covered in a thin, nearly transparent sac that hardly ever is open or broken.
What medications can cause omphalocele?
Women who use selective serotonin-reuptake inhibitors (SSRIs) during pregnancy are more likely to have a baby with omphalocele. SSRIs are usually found in medications like antidepressants. Obesity. Obesity in expectant mothers can also pose a risk to the fetus.
Is omphalocele more common in males or females?
A small type of omphalocele that involves only the protrusion of the intestines occurs in one in 5,000 babies, whereas a large type that sees a protrusion of the intestines, liver, and other abdomen organs happens to one in 10,000 babies. Boys have an omphalocele more often than girls.