What is the chemical structure of methyl salicylate?

What is the chemical structure of methyl salicylate?

C8H8O3

Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often associatively called “minty”, as it is an ingredient in mint candies.

How much methyl salicylate is toxic?

Ingestion of less than 150 mg/kg is usually not associated with systemic toxicity; 150–300 mg/kg may produce mild to moderate symptoms of hyperpnea and neurologic disturbances (lethargy and/or excitability). A dose of greater than 500 mg/kg of salicylate can result in severe hyperpnea, coma, and occasionally seizures.

What is the mechanism of methyl salicylate formation?

When salicylic acid is heated with methyl alcohol, the carboxyl group of salicylic acid is esterified producing a strong-smelling liquid ester (methyl salicylate). an alcohol and a carboxylic acid. The reaction is reversible and uses an acid as a catalyst.

Is methyl salicylate toxic to humans?

Methyl salicylate is the most poisonous form of the salicylate type of chemicals.

What functional group is methyl salicylate?

The given compound methyl salicylate is shown as: In the compound, the functional groups are alcohol (OH) and ester group (COO). The nature of the compound is acidic due to the presence of OH group.

What are the hazards of methyl salicylate?

Eye: May cause eye irritation.

What is a toxic salicylate level?

Salicylate levels greater than 100 mg/dL are considered severe toxicity and occur 12 to 24 hours after ingestion.

What is the pathophysiology of salicylate toxicity?

The principal pathophysiologic effect of toxic doses of salicylates are characterized by (1) stimulation of the respiratory center of the brain, leading to hyperpnea and respiratory alkalosis; (2) uncoupling of oxidative phosphorylation, leading to increased oxygen utilization and glucose demand, increased oxygen …

What kind of reaction is the conversion of methyl salicylate to salicylic acid?

saponification reaction
Methyl salicylate can be converted into salicylic acid using the saponification reaction. You will perform this reaction and will purify the product using crystallization.

What is the mechanism of toxicity of salicylic acid?

And while the pH of the urine in coma is c. 5.2, it is about 7.0-7.2 in salicylic acid poisoning. Odin’s conclusion from his observations, which are both extensive and thoroughgoing, is that the mechanism of salicylic acid poisoning is a toxic injury to the respiratory centre with a resulting hyperventilation.

How much salicylic acid is toxic?

Salicylate levels greater than 100 mg/dL are considered severe toxicity and occur 12 to 24 hours after ingestion. Damage to the basement membranes will cause cerebral and pulmonary edema. Patients may become obtunded and develop seizures.

What are two uses of methyl salicylate?

For acute joint and muscular pain, methyl salicylate is used as a rubefacient and analgesic in deep heating liniments. It is used as a flavoring agent in chewing gums and mints in small concentrations and added as antiseptic in mouthwash solutions.

Is methyl salicylate a carboxylic acid?

carboxylic acids
In methyl salicylate (oil of wintergreen), the COOH group of salicylic acid is esterified with methanol (CH3OH), whereas in acetylsalicylic acid (aspirin) the acid component of the ester is acetic acid, and salicylic acid contributes the phenolic ―OH group.

What is the other name of methyl salicylate?

oil of wintergreen
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3.
…
Methyl salicylate.

What happens if you swallow methyl salicylate?

Warning symptoms of methyl salicylate toxicity range from fatigue, nausea, hallucinations, dizziness, difficulty breathing, convulsions, ringing in the ears and vomiting.

What is the first symptom of salicylate toxicity?

Nausea, vomiting, diaphoresis, and tinnitus are the earliest signs and symptoms of salicylate toxicity. Other early symptoms and signs are vertigo, hyperventilation, tachycardia, and hyperactivity.

Does salicylate intoxication cause metabolic acidosis?

Salicylate poisoning can cause vomiting, tinnitus, confusion, hyperthermia, respiratory alkalosis, metabolic acidosis, and multiple organ failure.

What happens when you add HCl to methyl salicylate?

Upon acidification with HCl the carboxylic acid product precipitates out of solution. The ester methyl salicylate is the active odor component of “oil of wintergreen” and its distinctive smell is readily apparent. Many esters of carboxylic acids have fragrant odors.

Why the reaction is called O acetylation?

The term ‘acetylation’ is used to denote the organic chemical reactions in which a hydrogen atom belonging to a compound is substituted with an acetyl group (which is a functional group with the general formula CH3C=O). Usually, the products formed in acetylation reactions have acetoxy functional groups.

Why does salicylate intoxication causes respiratory alkalosis?

High levels of salicylates stimulate peripheral chemoreceptors and the central respiratory centers in the medulla causing increased ventilation and a respiratory alkalosis.

How does aspirin toxicity cause metabolic acidosis?

Aspirin directly stimulates cerebral respiratory centers and inhibits the citric acid cycle, causing uncoupling of oxidative phosphorylation which ultimately leads to lactic acidosis.

Can 2% salicylic acid cause toxicity?

What is another name for methyl salicylate?

Methyl salicylate

What is the equation of methyl salicylate?

C8H8O3Methyl salicylate / Formula

What does methyl salicylate do in the body?

This product is used to treat minor aches and pains of the muscles/joints (such as arthritis, backache, sprains). Menthol and methyl salicylate work by causing the skin to feel cool and then warm. These feelings on the skin distract you from feeling the aches/pains deeper in your muscles and joints.