What should I monitor with linagliptin?
Check with your doctor right away if you have a sudden and severe stomach pain, chills, constipation, nausea, vomiting, loss of appetite, fever, or lightheadedness. This medicine may cause hypoglycemia (low blood sugar). This is more common when this medicine is taken together with certain medicines.
Does linagliptin need renal adjustment?
Thus, linagliptin needs no dose adjustment in patients with impaired renal function (13,14). Dose adjustment is recommended for sitagliptin, saxagliptin, and vildagliptin in patients with creatinine clearance <50 mL/min, including those with ESRD requiring dialysis (12).
What are the side effects of linagliptin?
Incidence not known
- Bloating.
- hives, welts, itching, or skin rash.
- large, hard skin blisters.
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs.
- pains in the stomach, side, or abdomen, possibly radiating to the back.
- severe joint pain.
What is linagliptin indication?
Linagliptin is indicated for the treatment of type II diabetes in addition to diet and exercise 5. It should not be used to treat type I diabetes or in diabetic ketoacidosis.
Who should not take linagliptin?
Linagliptin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated).
What is the best time of day to take linagliptin?
You can generally take the tablet at a time of day to suit you, but it is best to take your doses at the same time of day each day. You can take these tablets either with or without food.
Is TRADJENTA safe in renal failure?
TRADJENTA is the only single-strength DPP-4 inhibitor that requires no dose adjustment regardless of renal function.
What is the best time to take linagliptin?
When is the best time to take linagliptin?
Can linagliptin cause low blood pressure?
Dizziness, lightheadedness, or fainting may occur with this medicine. This is more common if you have kidney disease, low blood pressure, or if you are taking a diuretic (water pill).
How quickly does linagliptin work?
Linagliptin starts to work within a few hours. You need to take it every day to make sure your blood sugar stays as stable as possible. You take linagliptin once a day. Most people have no side effects, or only minor ones, when taking linagliptin.
Who should not take Tradjenta?
TRADJENTA is contraindicated in patients with a history of a hypersensitivity reaction to linagliptin, such as urticaria, angioedema, or bronchial hyperreactivity [see Adverse Reactions 6.1]. Insulin secretagogues are known to cause hypoglycemia.
Can linagliptin cause kidney problems?
Linagliptin and placebo had little effect on renal function (median change in eGFR, −0.8 versus −2.2 ml/min/1.73 m2) and no drug-related renal failure occurred. The incidence of adjudicated cardiovascular events was similar in both groups [McGill et al.
Is tradjenta hard on kidneys?
Can Tradjenta cause side effects related to the kidneys? No, Tradjenta isn’t known to cause side effects related to the kidneys. It’s important to note that people with diabetes have an increased risk of kidney problems. This is because, over time, high blood sugar levels can damage the kidneys.
Can linagliptin cause heart failure?
In patients with type 2 diabetes mellitus and concomitant atherosclerotic vascular disease and/or diabetic kidney disease, the antihyperglycemic medication linagliptin did not affect risk for heart failure hospitalization or other associated heart failure–related complications.
Who should not take tradjenta?
Who should not take TRADJENTA?
Is linagliptin safe for heart patients?
In a patient population at very high risk for heart failure and its complications, linagliptin can be used without increasing the risk for hospitalization for heart failure.
Can TRADJENTA cause heart failure?
TRADJENTA has not been studied in patients with a history of pancreatitis, and it is unknown if using TRADJENTA increases the risk of developing pancreatitis in these patients. Heart Failure: Heart failure has been observed with two other members of the dipeptidyl peptidase-4 (DPP-4) inhibitor class.
Is TRADJENTA safe for kidneys?
SAN FRANCISCO – The dipeptidyl peptidase-4 inhibitor linagliptin (Tradjenta) is safe on the kidneys, the cardiovascular system, and in older people with type 2 diabetes, according to findings presented at the annual scientific sessions of the American Diabetes Association.