What are hydrogel nanoparticles?
Hydrogel nanoparticles—also referred to as polymeric nanogels or macromolecular micelles—are emerging as promising drug carriers for therapeutic applications. These nanostructures hold versatility and properties suitable for the delivery of bioactive molecules, namely of biopharmaceuticals.
Are hydrogels nanotechnology?
Nanostructured therapeutic materials The hydrogel nanocomposites are classified in accordance with incorporated nanomaterials. The mechanical and responsive properties are discussed as well as potential therapeutic applications.
Is hydrogel toxic to humans?
Based on behavior in a living organism, hydrogels can be non-toxic and toxic.
What does Pamam stand for?
Poly(amidoamine)
Poly(amidoamine), or PAMAM, is a class of dendrimer which is made of repetitively branched subunits of amide and amine functionality.
What are the methods of dendrimer synthesis?
In the different methods, dendrimer grows outward from a multifunctional core molecule. The core molecule reacts with monomer molecules containing one reactive and two dormant groups, giving the first-generation dendrimer. Then, the new periphery of the molecule is activated for reactions with more monomers.
What are the pharmacokinetic properties of dendrimers?
Pharmacokinetic properties are one of the most significant aspects that need to be considered for the successful biomedical application of dendrimers, for instance, drug delivery, imaging, photodynamic therapy, and neutron capture therapy. The diversity of potential applications of dendrimers in medicine results in increasing interest in this area.
What makes dendrimers a good choice in the medical field?
These varied characteristics make dendrimers a good choice in the medical field, and this review covers their diverse applications. Dendrimers are nano-sized, radially symmetric molecules with well-defined, homogeneous, and monodisperse structure consisting of tree-like arms or branches [ 1 ].
Are dendrimers the building blocks of nanoscale synthetic organic chemistry?
Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic organic chemistry. Aldrichimica Acta. 2004;9:39–57.