What is the pharmacology of amoxicillin?
Pharmacology. Amoxicillin (α-amino-p-hydroxybenzyl penicillin) is a semisynthetic derivative of penicillin with a structure similar to ampicillin but with better absorption when taken by mouth, thus yielding higher concentrations in blood and in urine. Amoxicillin diffuses easily into tissues and body fluids.
What are the physical properties of amoxicillin?
AmoXicillin trihydrate is a white or almost white crystalline powder. Amoxicillin sodium salt is a white or almost white powder, sometimes with a pinkish tinge. As normally produced it is amorphous and hygroscopic.
What is 500mg of amoxicillin used for?
It is used to treat bacterial infections, such as chest infections (including pneumonia) and dental abscesses. It can also be used together with other antibiotics and medicines to treat stomach ulcers. It’s often prescribed for children, to treat ear infections and chest infections.
What is the mechanism of action amoxicillin?
Mechanism of Action:
Exerts bactericidal activity via inhibition of bacterial cell wall synthesis by binding one or more of the penicillin binding proteins (PBPs). Exerts bacterial autolytic effect by inhibition of certain PBPs related to the activation of a bacterial autolytic process.
What are the side effects of amoxicillin 500mg?
Side Effects
- Abdominal or stomach cramps or tenderness.
- back, leg, or stomach pains.
- black, tarry stools.
- blistering, peeling, or loosening of the skin.
- bloating.
- blood in the urine.
- bloody nose.
- chest pain.
What is the other name for amoxicillin?
Amoxicillin is available as brand-name drugs called Amoxil and Larotid.
What is the composition of amoxicillin?
The active ingredient is Amoxicillin (as amoxicillin trihydrate) The other ingredients are Magnesium Stearate (E572) and Colloidal Anhydrous Silica. Amoxicillin 250mg and 500mg capsule shells contain Gelatin, Carmoisine (E122), Quinoline Yellow (E104), Titanium Dioxide (E171), and Iron Oxide Yellow (E172).
What is another name for amoxicillin?
Amoxicillin is available under the following different brand names: Amoxil, Moxatag, and Trimox.
What are the indications of amoxicillin?
Amoxicillin alone is indicated to treat susceptible bacterial infections of the ear, nose, throat, genitourinary tract, skin, skin structure, and lower respiratory tract.
What is the most common side effect of amoxicillin?
The most common amoxicillin side effects are nausea, vomiting, and diarrhea. These usually go away after you finish taking the medication. Contact your healthcare provider right away if you experience any serious side effects, such as severe diarrhea or signs of an allergic reaction.
What are the 5 mechanisms of action of antibiotics?
Five Basic Mechanisms of Antibiotic Action against Bacterial Cells:
What are the most common side effects of amoxicillin?
What is the contraindications of amoxicillin?
Amoxicillin is contraindicated in patients with known serious hypersensitivity to amoxicillin or to other drugs in the same class (i.e., penicillin hypersensitivity) or patients who have demonstrated anaphylactic reactions to beta-lactams (i.e., cephalosporin hypersensitivity or carbapenem hypersensitivity).
What are side effects of amoxicillin?
What are the contraindications of amoxicillin?
What infections do amoxicillin treat?
Amoxicillin is a penicillin antibiotic that fights bacteria. Amoxicillin is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.
What are the 7 main classes of antibiotics?
Classes of antibiotics include the following:
- Aminoglycosides.
- Carbapenems.
- Cephalosporins.
- Fluoroquinolones.
- Glycopeptides and lipoglycopeptides.
- Macrolides.
What are the 4 main classes of antibiotics?
Antibiotic class defines a set of related antibiotics. State-level rates of penicillins, macrolides, cephalosporins, and fluoroquinolones are displayed. Also displayed are all antibiotic classes, which include these four classes plus additional classes not available for release at the state level.
What is the brand name of amoxicillin?
What are the properties of antibiotics?
Antibiotics have various mechanisms of action, such as cell wall synthesis suppression, nucleic acid synthesis inhibition, cell membrane alternation, protein synthesis suppression, and DNA inhibition, depended on different functional agents of the molecule.
What are the side effects with amoxicillin?
What are 5 characteristics of an ideal antibiotic?
An ideal antimicrobic: – soluble in body fluids, – selectively toxic, – nonallergenic, – reasonable half life (maintained at a constant therapeutic concentration) – unlikely to elicit resistance, – has a long shelf life, – reasonably priced.
What medications interact with amoxicillin?
Most frequently checked interactions
- Aspirin Low Strength (aspirin)
- Augmentin (amoxicillin / clavulanate)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Cymbalta (duloxetine)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lexapro (escitalopram)
What are the ideal properties of antibiotics?
An ideal antibiotic is an antibacterial agent that kills or inhibits the growth of all harmful bacteria in a host, regardless of site of infection without affecting beneficial gut microbes (gut flora) or causing undue toxicity to the host.
What are the properties of antibacterial agents?
Antibacterial drugs can be either bacteriostatic or bactericidal in their interactions with target bacteria. Bacteriostatic drugs cause a reversible inhibition of growth, with bacterial growth restarting after elimination of the drug. By contrast, bactericidal drugs kill their target bacteria.