What is conjugated estrogen cream used for?
Conjugated estrogens vaginal cream is used to treat changes in and around the vagina (such as vaginal dryness, itching, and burning) caused by low estrogen levels or menopause. It is also used to treat vaginal pain during sexual intercourse.
Why has Premarin cream been discontinued?
A government study of Wyeth’s hormone replacement drugs, Prempro and Premarin, was discontinued in 2002 when it became apparent that taking Prempro heightened the risk of breast cancer, coronary heart disease, stroke, and pulmonary embolism, and that Premarin increased risk of stroke.
Can Premarin be applied topically?
Premarin® Vaginal Cream is administered intravaginally or topically in a cyclic regimen (daily for 21 days and then off for 7 days). Generally, women should be started at the 0.5g daily dosage strength.
Who should not use Premarin cream?
You should not use Premarin Vaginal Cream if you have: undiagnosed vaginal bleeding, liver disease, a bleeding disorder, if you will be having major surgery, or if you have ever had a heart attack, a stroke, a blood clot, or cancer of the breast, uterus/cervix, or vagina.
What are the risks of using estrogen cream?
Side Effects
- Breast pain.
- enlarged breasts.
- itching of the vagina or genitals.
- stinging or redness of the genital area.
- thick, white vaginal discharge without odor or with a mild odor.
What happens if you use too much estrogen cream?
Overdosage of estrogen may cause nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue, and withdrawal bleeding may occur in women.
Is there a generic substitute for Premarin cream?
Premarin (conjugated estrogens) vaginal cream eases menopause symptoms by replacing the estrogen naturally lost during menopause. There is no generic version of Premarin available. You can save on Premarin cream and tablets by using manufacturer incentives and exploring Premarin alternatives.
How do you apply Premarin cream topically?
Lie on back with knees drawn up. To deliver medication, gently insert applicator deeply into vagina and press plunger downward to its original position. Screw nozzle end of applicator onto tube.
How long should a woman use Premarin cream?
PREMARIN Vaginal Cream is administered intravaginally in a cyclic regimen (daily for 21 days and then off for 7 days). Generally, women should be started at the 0.5 g dosage strength. Dosage adjustments (0.5 to 2 g) may be made based on individual response [see Dosage Forms and Strengths (3)].
What is the best place to apply estrogen cream?
Carefully spread the cream into the vaginal/urethral area. As the cream is spread, make sure to cover the opening and just inside of the vagina as this is where the majority of estrogen receptors are located; however, it is not necessary to push the cream high into the vagina.
Can you get a yeast infection from using Premarin cream?
Fluid retention. Vaginal yeast infection. Reactions from inserting PREMARIN Vaginal Cream, such as vaginal burning, irritation, and itching.
Does estrogen cream make you gain weight?
Because estrogen affects how your body distributes fat, low estrogen levels can contribute to gaining fat in your belly area. However, estrogen replacement therapy can help your body redistribute this fat to different areas on your body, rather than your abdominal area.
Can vaginal atrophy be reversed?
Currently, estrogen replacement is the best way to reverse vaginal atrophy and GSM. Not every woman will be able to use this treatment option, however. Concerns about the long-term effects of increased estrogen sometimes discourage doctors from prescribing it.
Can u buy estrogen cream over the counter?
Yes, you can buy OTC estrogen creams without a prescription from your healthcare provider. However, you shouldn’t try to substitute OTC estrogen creams for prescription estrogen products. If you’re looking for vaginal estrogen creams for vaginal dryness, these aren’t available for OTC purchase.
How safe is topical estrogen cream?
Although estrogen replacement had been linked to an increased risk of cardiovascular disease and cancers, a landmark new study demonstrates no rise in risk for women using topical estrogen for relief of genitourinary syndrome.
When is the best time of day to apply estrogen cream?
It is usually applied once a day. Estradiol emulsion should be applied in the morning. Estradiol gel may be applied at any time of day, but should be applied at around the same time of day every day.
What happens if you use too much Premarin cream?
Overdosage of estrogen may cause nausea, vomiting, breast tenderness, abdominal pain, drowsiness and fatigue, and withdrawal bleeding may occur in women. Treatment of overdose consists of discontinuation of PREMARIN therapy with institution of appropriate symptomatic care.
Where do you apply estrogen cream?
If you are using estradiol gel, you should apply it in a thin layer to one arm, from the wrist to the shoulder. If you are using estradiol emulsion, you should apply it to both thighs and calves (lower legs). Do not apply estradiol gel or emulsion to your breasts.
How do you get rid of dryness down there?
For vaginal dryness by itself, I recommend trying over-the-counter moisturizers and lubricants.
- Vaginal moisturizers add moisture around and inside the vagina. There are two types.
- Lubricants decrease discomfort during intercourse. Sexually active women should use lubricants in addition to a vaginal moisturizer.
What is an alternative to estrogen cream?
Vivelle dot patches, Estrace 0.01% cream, Paxil CR, Neurontin, and Catapres are some estradiol alternatives. Get the full list here. Estradiol, a form of estrogen, is a female sex hormone drug available by prescription in a variety of dosage forms.
How long does it take for topical estrogen to work?
What topical estrogen treatments are available? Topical vaginal estrogen treatment can produce great improvement in just eight to 12 weeks. It can be applied in different ways: Suppositories inserted in the vagina with an applicator two to three times a week at bedtime.
How long is it safe to use Premarin cream?
How much should I use? Your doctor will prescribe the dosage that’s right for you. Estrogens, with or without a progestin, should be used at the lowest effective dose for the shortest duration of time. A single tube of Premarin Vaginal Cream can last up to 6 months depending on the dosing regimen prescribed.