Why is OKC called KCOT?
In recent years, World health organization (WHO) recommended the term cystic neoplasm (now known as keratocystic odontogenic tumor (KCOT)) for this lesion, as it better reflects aggressive clinical behavior, histologically high mitotic rate and association with genetic and chromosomal abnormalities.
What is a Keratocyst?
Introduction. Odontogenic keratocysts (OKCs), first described by Philipsen in 1956 [1], are benign intraosseous lesions of odontogenic origin that account for about 10% of jaw cysts. They are characterised by an aggressive behaviour with a relatively high recurrence rate [2].
What causes odontogenic Keratocysts?
Odontogenic keratocysts (OKCs) are generally thought to be derived from remnants of the dental lamina (rests of Seres), traumatic implantation or down growth of the basal cell layer of the surface epithelium, or reduced enamel epithelium of the dental follicle.
Who coined the term OKC?
Over 50 years ago, Philipsen (1956) coined the name “odontogenic keratocyst” (OKC) to characterize a category of odontogenic cysts with a distinctive histological appearance.4 It makes up around 11% of jaw cysts.5 (Figure 1)
Is Keratocyst cancerous?
The keratocystic odontogenic tumor is a benign developmental tumor with many distinguishing clinical and histologic features. These characteristics are reviewed in the setting of a typical presentation. The newly acknowledged neoplastic potential and its implications for treatment strategies are also discussed.
How are Keratocysts treated?
Depending on other studies KCOT can be conservatively treated with enucleation and application of Carnoy’s solution or cryotherapy. This can be used specially in the large lesions that when treated with resection, the continuity of the jaw will be interrupted.
How fast does odontogenic Keratocyst grow?
Results: The growth rate of 8 recurrent cysts was 0.7 mm to 22.0 mm/year with average of 4.90 mm per year. Moreover, the growth rate of recurrent cysts in early postoperative period was much faster than those in late period, and no sclerotic margin was observed around the radiolucency areas.
How are odontogenic keratocysts diagnosed?
Diagnosis is usually radiological. However, definitive diagnosis is through biopsy. Aspirational biopsy of odontogenic keratocysts contains a greasy fluid which is pale in colour and contains keratotic squames. Protein content of cyst fluid below 4g% is diagnostic of odontogenic keratocysts.
What is Cementoblastoma?
True cementoma, now known as cementoblastoma, is a benign odontogenic tumor commonly presenting with painful swelling of the alveolar ridges (1). Such lesions have a predilection for the mandible and are primarily associated with the mandibular first molar.
Can odontogenic Keratocyst be cured?
Depending on other studies KCOT can be conservatively treated with enculation and application of Carnoy’s solution or cryotherapy. This can be used specially in the large lesions that when treated with resection, the continuity of the jaw will be interrupted.
Is Odontogenic Keratocyst a tumor?
The keratocystic odontogenic tumor (KCOT), formerly known as the odontogenic keratocyst (OKC), received its new designation in order to better convey its neoplastic nature [1]. It is a benign developmental odontogenic tumor with many distinguishing clinical and histologic features.
What is the difference between cementoma and cementoblastoma?
Cementomas develop as cells that generate cementum, or cementoblasts uncontrollably proliferate at the apex of a tooth root. Cementoblasts that form the cementum typically cease activity and become cementocytes.
What is an Odontome?
An odontome is a growth in which both epithelial and mesenchymal cells exhibit complete differentiation with the result that functional ameloblasts and odontoblasts form enamel and dentin.[1]
Is OKC cancerous?
OKC is a benign, clinically significant cystic tumor of odontogenic origin.
How are odontogenic Keratocysts removed?
Odontogenic keratocysts can initially be treated with incisional biopsy and decompression by installing a polyethylene drain to allow subsequent reduction of the cystic cavity size, resulting in thickening of the capsule, which allows a later easy removal withapparently lower relapse rate (Waldron).
Why is cementoblastoma painful?
Cementoblastoma has, only rarely, been associated with a primary or impacted tooth [1–4]. All cases are connected to the root of the involved tooth [1–7]. Cementoblastoma commonly presents with pain and associated swelling due to bony expansion of the buccal and lingual aspects of the alveolar ridges [1–5].
Should odontomas be removed?
While an odontoma is a tumor, it’s a benign one and not uncommon. That alone is great news! However, odontomas usually require surgical removal. They’re made up of dental tissue that resembles abnormal teeth or calcified mass that invade the jaw around your teeth and could affect how your teeth develop.
Why is OKC recurrence so high?
There are several possible reasons why OKC recur so frequently and require meticulous surgical planning and execution. The first of these is related to their tendency to multiplicity in some patients, including the occurrence of satellite cysts, which may be retained during an enucleation procedure.
What is the difference between Cementoma and cementoblastoma?
Does cementoblastoma cause root resorption?
On x ray, characteristic findings of cementoblastoma include well defined, markedly radiopaque mass, radiolucent peripheral “line” which overlies and obliterates the tooth root, apparent external root resorption, and severe hypercementosis.
Is an odontoma cancerous?
Odontomas are not cancer. They are considered benign tumors, though in humans they are often surgically removed.
What causes an odontoma?
Odontomas have been extensively reported in the dental literature, and the term refers to tumors of odontogenic origin. Though the exact etiology is still unknown, the postulated causes include: local trauma, infection, inheritance and genetic mutation.
Who treats odontogenic Keratocyst?
Treatment of odontogenic keratocyst (OKC) is one of the highly controversial protocols among oral and maxillofacial surgeons. Treatment modalities range from simple enucleation in the case of lesions that are less than 1 cm to extensive resection in the case of cysts that extend into the skeletal base.
How can you tell the difference between Ameloblastoma and OKC?
Most OKCs showed smooth border and unilocular shape, while most ameloblastomas showed scalloped border and multilocular shape. Compared with ameloblastomas, OKCs showed greater frequency to be associated with impacted tooth, and were unlikely to cause tooth displacement and root resorption.
Should cementoblastoma be removed?
The cementoblastoma has been described as a benign, solitary, slow-growing lesion, although there have been reports of aggressive behaviour. Due to the benign neo plastic nature of the lesion, the treatment of choice is complete removal of the lesion with extraction of the associated tooth.