What does the Antennapedia gene cause?
Antennapedia (abbreviated Antp) is a Hox gene first discovered in Drosophila which controls the formation of legs during development. Loss-of-function mutations in the regulatory region of this gene result in the development of the second leg pair into ectopic antennae.
What is the Antennapedia complex?
The Antennapedia complex (ANT-C) is one of two Hox gene complexes. Hox genes encode homeodomain transcription factors. ANT-C controls the identity of segments that contribute to the head and the anterior thorax. ANT-C homeotic genes show colinearity in their expression patterns with the exception of pb.
What happens when the gene Antennapedia is expressed in the head of the fly?
It is known that overexpressing Antennapedia in the head induces antenna-to-leg as well as head-to-thorax transformation and eye reduction. At present, little is known about the exact molecular mechanism causing these phenotypes.
Is antennapedia dominant or recessive?
Most of the early mutations were dominant – ie only one copy of the mutant gene is required to affect a transformation (e.g. Antennapedia: antenna-to-leg). Later, recessive mutations Antennapedia were discovered, which cause the reverse transformation (leg-to-antenna).
Is Antennapedia dominant or recessive?
What is homeodomain protein?
The homeodomain is a highly conserved 60‐amino‐acid protein domain that is encoded by the homeobox and is found in organisms as diverse as mammals, insects, plants and yeast. Homeodomains function as DNA binding domains and are found in many transcription factors that control development and cell fate decisions.
What is the function of a homeodomain?
What is the function of Hox genes during development quizlet?
What do hox genes act like? Genetic switches that turn on and off other genes. So control the timing and route of development.