What is an event free survival?
Listen to pronunciation. (eh-VENT … ser-VY-vul) In cancer, the length of time after primary treatment for a cancer ends that the patient remains free of certain complications or events that the treatment was intended to prevent or delay.
What is the difference between disease free survival and recurrence free survival?
Unlike progression-free survival in the advanced cancer setting, which refers to time from treatment to disease progression (or death) in patients who already have measurable cancer in their bodies, DFS refers to time from treatment until the recurrence of disease (or death) after undergoing curative-intent treatment.
What is EFS and OS?
In contrast to OS, where death is the only event of interest, EFS is a composite end point that includes death resulting from any cause, failure to achieve complete remission (CR), and relapse from CR as events.
What is the difference between PFS and DFS?
Disease free survival While PFS is used as a clinical endpoint for treatments that are used to manage more advanced, metastatic malignancies, DFS is used as a clinical endpoint for adjuvant treatments after definitive surgery or radiotherapy.
Is TTP the same as PFS?
Time to progression (TTP) does not count patients who die from other causes but is otherwise a close equivalent to PFS (unless there are many such events). The FDA gives separate definitions and prefers PFS.
What is the difference between disease specific survival and overall survival?
Ultimately, patients care about 1 of 2 things: living longer or living better. Overall mortality directly measures living longer, while disease-specific mortality measures only death due to the target cancer.
What is EFS in AML?
Event-free survival was defined by: • Creutzig et al. (227) in a study of AML, defined EFS as early death, resistant leukemia, relapse, secondary malignancy, or death resulting from any cause.
How is disease free survival calculated?
The OS was defined as the length of time, in months, from the date of surgery to the date of last follow-up or death. The DFS was defined as the length of time, in months, from the date of surgery to the date of last follow-up or the local and/or distant recurrence.
What is disease free survival rate?
The measure of time after treatment during which no sign of cancer is found. This term can be used for an individual or for a group of people within a study. This term is usually used in the context of scientific research. After Treatment.
What is disease specific survival?
(dih-ZEEZ-speh-SIH-fik ser-VY-vul rayt) The percentage of people in a study or treatment group who have not died from a specific disease in a defined period of time. The time period usually begins at the time of diagnosis or at the start of treatment and ends at the time of death.
What does disease survival mean?
The percentage of people in a study or treatment group who have not died from a specific disease in a defined period of time. The time period usually begins at the time of diagnosis or at the start of treatment and ends at the time of death.
Does disease-free survival include death?
Disease-free survival (DFS) is defined as the time from randomization to recurrence of tumor or death, and it is typically used in the adjuvant treatment setting.
What is EFS rate?
The measure of time after treatment that a group of people in a clinical trial has not had cancer come back or get worse. This term is also usually used in the context of scientific research.
What is meant by disease-free?
disease-free (not comparable) free of disease, not having, carrying, or suffering from any disease.
What is difference between health and disease-free?
Technically, being healthy is a state of being fit and free of physical and mental illness. Both being healthy and being disease-free are normal human states. A disease-free person can be healthy, but a healthy person does not have to be disease-free.
What is the difference between disease-specific survival and overall survival?
What does disease-free mean?
What does event-free survival mean?
Definition of event-free survival – NCI Dictionary of Cancer Terms – National Cancer Institute In cancer, the length of time after primary treatment for a cancer ends that the patient remains free of certain complications or events that the treatment was intended to prevent or delay.
What is the meaning of disease free survival?
Disease-free survival (DFS) is a number that tells the chances of staying free of a disease or cancer after a particular treatment. It is the percentage of individuals in the treatment group who are likely to be free of the signs and symptoms of a disease after a specified duration of time. Furthermore, how is overall survival calculated?
What is the difference between disease free survival and hazard ratio?
Disease free survival: time to disease reoccurring. Measuring the length of time after treatment during which no disease is found. The Hazard ratio is the ratio of the probability of an event (death or progression) in the experimental arm to the probability in the comparator arm.
What is disease-free survival (DFS)?
Edward L. Korn, Boris Freidlin, in Abeloff’s Clinical Oncology (Sixth Edition), 2020 Disease-free survival (DFS) is defined as the time from randomization to recurrence of tumor or death, and it is typically used in the adjuvant treatment setting.