What is Gemzar made from?
Vials of Gemzar contain either 200 mg or 1 g of gemcitabine HCl (expressed as free base) formulated with mannitol (200 mg or 1 g, respectively) and sodium acetate (12.5 mg or 62.5 mg, respectively) as a sterile lyophilized powder. Hydrochloric acid and/or sodium hydroxide may have been added for pH adjustment.
What kind of chemo is Gemzar?
Gemzar is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. Gemzar is classified as an antimetabolite.
What cancer is Gemzar used for?
Gemcitabine is a chemotherapy drug used as a treatment for different types of cancer, including bladder and breast cancer. Depending on your cancer type you might have gemcitabine on its own or in combination with other cancer drugs. You might also have it alongside radiotherapy treatment.
What is survival rate of patients getting gemcitabine?
Background: Adjuvant chemotherapy following curative resection is the standard treatment for pancreatic adenocarcinoma (PC). Randomized clinical trials using gemcitabine have shown a median overall survival (mOS) of 2 years and a 5-year survival rate of 15-20%.
How toxic is gemcitabine?
Gemcitabine is associated with a wide spectrum of lung toxicities, ranging from dyspnea 25% of patients to severe pulmonary toxicity in up to 5% of patients.
How good is Gemzar?
Gemzar has an average rating of 7.8 out of 10 from a total of 5 ratings on Drugs.com. 40% of reviewers reported a positive experience, while 0% reported a negative experience. Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content.
How effective is Gemzar?
Survival at 1 year was 47% for patients treated with Taxotere®/Gemzar®, and 42% for those treated with Platinol®/vinorelbine. Progression-free survival was approximately 4 months for both groups of patients.
How long do gemcitabine side effects last?
Nausea and vomiting may occur after your treatment and may last for 24 hours.
How long is Gemzar infusion?
The recommended dose of Gemzar is 1000 mg/m² as an intravenous infusion over 30 minutes on Days 1 and 8 of each 21-day cycle, in combination with carboplatin AUC 4 intravenously after Gemzar administration on Day 1 of each 21- day cycle.
How many cycles of gemcitabine can you have?
You usually have between 4 to 6 cycles of treatment taking from 3 to 6 months. You have gemcitabine as a drip into your bloodstream over 30 minutes.