What is the medicine gemfibrozil used for?
Gemfibrozil is used together with a proper diet to treat high cholesterol and triglyceride (fat) levels in the blood. This may help prevent the development of pancreatitis (inflammation or swelling of the pancreas) caused by high levels of triglycerides in the blood.
What are the side effects of bezafibrate?
Side effects of Bezafibrate include:
- Stomach upset.
- Stomach pain.
- Gas.
- Nausea.
- Itchy skin.
- Redness.
- Headache.
- Dizziness.
What is Bezafibrato in English?
Bezafibrate (marketed as Bezalip and various other brand names) is a fibrate drug used as a lipid-lowering agent to treat hyperlipidaemia. It helps to lower LDL cholesterol and triglyceride in the blood, and increase HDL. Bezafibrate. Clinical data. AHFS/Drugs.com.
What type of drug is clofibrate?
Clofibrate is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Clofibrate therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.
Will gemfibrozil help lose weight?
Some people who take gemfibrozil (Lopid) might experience weight loss, though this is not a common effect of the medication. Remember that it is best to maintain a healthy diet and lifestyle in order to lose weight, and to get the best effect from taking gemfibrozil (Lopid).
Does gemfibrozil affect the kidneys?
Even when these individuals were excluded, no clinically significant effect of gemfibrozil on kidney function was observed. Conclusion: Gemfibrozil does not appear to exert a clinically relevant effect on rates of kidney function loss in individuals with moderate CRI, low HDL-C levels, and concomitant coronary disease.
What is the safest drug to take for high cholesterol?
Fortunately, most side effects are mild and disappear promptly when the statin is stopped. In some cases, the problems will resolve simply by reducing the dose or switching to another statin, but care is required. Still, all in all, the statins are the safest and best tolerated of all cholesterol-lowering medications.
Does bezafibrate affect kidney function?
Bezafibrates cause moderate, reversible impairment in renal function in patients without prior renal disease.
What are the most common side effects of atorvastatin?
Common side effects
- Feeling sick (nausea) or indigestion. Stick to simple meals and do not eat rich or spicy food.
- Headaches. Make sure you rest and drink plenty of fluids.
- Nosebleeds.
- Sore throat.
- Cold-like symptoms, such as a runny nose, blocked nose or sneezing.
- Constipation or farting (flatulence)
- Diarrhoea.
Does bezafibrate cause muscle pain?
Check with your doctor as soon as possible if any of the following side effects occur: decreased urine production. dizziness. muscle pain, tenderness, or weakness, especially if accompanied by fever and feeling unwell.
Why was clofibrate discontinued?
It was patented in 1958 by Imperial Chemical Industries and approved for medical use in 1963. Clofibrate was discontinued in 2002 due to adverse effects. A PPAR modulator which activates the peroxisome proliferator-activated receptor- alpha . A substance used to lower plasma cholesterol levels.
What is clofibrate used for?
Clofibrate is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. This may help prevent medical problems caused by such substances clogging the blood vessels.
Does gemfibrozil make you tired?
dizziness, drowsiness; blurred vision; muscle or joint pain; or. loss of interest in sex, impotence.
What happens when you stop taking gemfibrozil?
When you stop taking this medicine, your blood cholesterol levels may increase again. Your doctor may want you to follow a special diet to help prevent this from happening. Do not take other medicines unless they have been discussed with your doctor.
Does gemfibrozil cause memory loss?
Gemfibrozil, used for elevated cholesterol, also is reported to cause memory disorders, as are the more commonly used class of cholesterol drugs, the statins.
What is the new treatment for high cholesterol?
There’s a new drug called Nexletol, and it’s used for people with the highest risk. That’s people with genetic or familial high cholesterol or those who have heart disease and further need to lower their cholesterol. It’s called bempedoic acid. It works to lower the cholesterol your liver makes.
What drinks are good for cholesterol?
Best drinks to improve cholesterol
- Green tea. Green tea contains catechins and other antioxidant compounds that seem to help lower “bad” LDL and total cholesterol levels.
- Soy milk. Soy is low in saturated fat.
- Oat drinks.
- Tomato juice.
- Berry smoothies.
- Drinks containing sterols and stanols.
- Cocoa drinks.
- Plant milk smoothies.
Can you take bezafibrate long term?
Following this advice will also help you to reduce your risk of developing heart and blood vessel disease. Treatment with bezafibrate is usually long-term unless you experience an adverse effect. Continue to take the tablets unless you are advised otherwise by your doctor.
Can you take bezafibrate at night?
The recommended daily dose for Fibrazate® XL 400mg Tablets is one tablet, equivalent to 400mg bezafibrate, after a meal either in the morning or at night.
What should I avoid when taking atorvastatin?
While taking atorvastatin (Lipitor), avoid high-fat and high-cholesterol foods as part of your overall treatment. You should avoid large quantities of grapefruit or grapefruit juice, which can increase the risk of serious side effects. Also, avoid excess alcohol use, as this may cause serious liver problems.
What foods to avoid while taking statins?
Grapefruit juice is the only food or drink that has a direct interaction with statins. Statins do not directly interact with any food but people taking statins should moderate their intake of saturated fats to help lower their LDL cholesterol and overall risk of cardiovascular disease.
What is the brand name of clofibrate?
Clofibrate is available with a prescription under the brand name Atromid-S. Other brand or generic formulations may also be available.
Can fenofibrate prevent strokes?
Although fenofibrate decreases the levels of fatty substances in the blood, it has not been shown to decrease the risk of heart attacks or strokes. Fenofibrate is in a class of medications called antilipemic agents.
Can gemfibrozil cause weight gain?
Results: With gemfibrozil significantly more subjects lost weight (51.7% versus 38.6%, P<0.0001) and significantly fewer subjects gained weight (42.5% versus 54.0%, P<0.0001) than with placebo.
How can I lower my triglycerides in 7 days?
7-Day Diet to Lower Triglycerides
Classic oats with low-fat or plant milk, topped with berries and seeds. Vegetable and lentil soup with whole-grain crackers. Curry made with tofu, and butternut squash served over cauliflower rice. Poached egg with salmon and whole-grain rye toast.
What is the drug lovastatin used for?
Lovastatin is used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood. This medicine may also help prevent medical problems (eg, chest pain, heart attack, stroke) caused by fat clogging the blood vessels.
What is generic for Zocor?
Zocor is available as a generic drug called simvastatin. Lipitor is available as a generic drug called atorvastatin. A generic drug is an exact copy of the active drug in a brand-name medication.
What are side effects of gemfibrozil?
Common Side effects of Gemfibrozil include:
- Indigestion/heartburn.
- Stomach/abdominal pain.
- Atrial fibrillation.
- Diarrhea.
- Fatigue.
- Nausea.
- Vomiting.
- Eczema.
What is the most serious side effect of lovastatin?
Important warnings. Serious muscle damage warning: Using lovastatin raises your risk of serious muscle problems. These problems include myopathy, with symptoms that include muscle pain, tenderness, or weakness. Myopathy can lead to rhabdomyolysis.
Why do statins have to be taken at night?
So, why do people take statins at night? Many statins work more effectively when they are taken at night. This is because the enzyme which makes the cholesterol is more active at night. Also, the half-life, or the amount of time it takes for half the dose to leave your body, of some statins is short.
Do you have to take Zocor at night?
Simvastatin is probably best taken at night because concentrations of total cholesterol and of low density lipoprotein are significantly greater when it is taken in the morning.
Does gemfibrozil affect your kidneys?
In rare cases, gemfibrozil can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.
What foods to avoid when taking lovastatin?
Avoid eating foods high in fat or cholesterol, or lovastatin will not be as effective. Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage. Grapefruit may interact with lovastatin and lead to unwanted side effects.
Can I drink coffee while taking statin?
Caffeine is a nonspecific adenosine receptor blocker, and thus drinking CC may block the myocardial protective effects of statins.
When Should statins be stopped in elderly?
Do not start a statin in patients ages ≥ 75 years who do not have known vascular disease or type 2 diabetes; start or continue a statin in all patients ages 75 to 84 with type 2 diabetes to prevent cardiovascular events and mortality; and start or continue a statin in patients ages > 75 years who have known vascular …
Why clofibrate and warfarin should not be given together?
Clofibrate can increase the effects of warfarin and cause you to bleed more easily. If your doctor prescribes these medications together, you may need a dose adjustment in addition to more frequent monitoring of your prothrombin time or International Normalized Ratio (INR) to safely use both medications.