What is the uronic acid pathway?
Uronic acid pathway is an alternative oxidative pathway for glucose metabolism. It catalyzes the conversion of glucose to glucuronic acid, ascorbic acid, and pentoses. It does not lead to the formation of ATP.
Which vitamin is produced in the uronic acid pathway?
Vitamin C
Vitamin C is synthesized via the uronic acid pathway in most animals except primates, fish, flying mammals, songbirds, and guinea pigs. L-Gulonate serves as a branch point between the uronic acid pathway and the hexose monophosphate shunt through formation of D-Xylulose.
Where does uronic acid pathway occur?
In liver, the uronic acid pathway catalyzes the conversion of glucose to glucuronic acid, ascorbic acid (except in human beings and other species for which ascorbate is a vitamin, vitamin C), and pentoses (Figure 20–4).
Which of the following is not synthesized in the uronic acid pathway?
In man and other primates as well as guinea pigs ascorbic acid cannot be synthesized. The enzyme L-gulonolactone oxidase which converts gulonate to ascorbic acid is absent in them. Therefore, vitamin C has to be supplemented in the diet for these animals.
Why is uronic acid important?
The uronic acids that are present in hemicelluloses also play an important role in the structure of the lignocellulosic matrix. For example, ester linkages between 4-O-Methyl-D-Glucuronic Acid and the lignin polymer have been documented.
How uronic acid is formed?
Uronic acids are derived from the oxidation of the hydroxyl group on C6 of aldoses. The main uronic acids found in wines made from healthy grapes are d-galacturonic acid and d-glucuronic acid, whose concentrations range from 40 to 400 mg/L and from 0 to 60 mg/L, respectively.
What does uronic acid mean?
Definition of uronic acid
: any of a class of acidic compounds of the general formula HOOC(CHOH)nCHO that contain both carboxylic and aldehydic groups, are oxidation products of sugars, and occur combined in many polysaccharides and in urine.