What explains feedback inhibition of a biochemical pathway?
Feedback Inhibition in Metabolic Pathways
Feedback inhibition is when a reaction product is used to regulate its own further production. Cells have evolved to use feedback inhibition to regulate enzyme activity in metabolism, by using the products of the enzymatic reactions to inhibit further enzyme activity.
What is feedback inhibition of a metabolic pathway?
Another way a metabolic pathway can be controlled is by feedback inhibition. This is when the end product in a metabolic pathway binds to an enzyme at the start of the pathway. This process stops the metabolic pathway and so prevents further synthesis of the end product until the end product concentration decreases.
What is feedback inhibition give an example?
A simple example of feedback inhibition is a thermostat connected to a heater. A sensor detects the temperature in the room, and when the temperature reaches a predetermined set point, the thermostat signals the furnace to shut off.
What is feedback inhibition in enzyme activity?
Feedback inhibition is a form of allosteric regulation in which the final product of a sequence of enzymatic reactions accumulates in abundance. With too much of this product produced, the final product binds to an allosteric site on the first enzyme in the series of reactions to inhibit its activity.
What are the main principles of feedback inhibition?
Feedback inhibition involves the use of a reaction product to regulate its own further production (Figure 11). The cell responds to an abundance of the products by slowing down production during anabolic or catabolic reactions.
What is feedback inhibition and its types?
Feedback inhibition (also known as End-product inhibition) is a type of negative feedback that can be used to control metabolic pathways. End-product inhibition occurs when a reaction’s final product blocks an enzyme from a previous phase in the sequence.
Which one is a typical example of feedback inhibition?
An example of feedback inhibition is the inhibition of the activity of the enzyme hexokinase by glucose 6-phosphate in glycolysis. This enzyme catalyses conversion of glucose into glucose 6-phosphate but as the reaction proceeds, increase in concentration of glucose 6-phosphate inhibits the activity of hexokinase.
Which of the following is the best example of feedback inhibition?
What is the best example of feedback inhibition? High ATP concentrations in the cell inhibit the action of phosphofructokinase, the third enzyme of glycolysis.
Which of the following is a typical example of feedback inhibition?
Which of the following best describes feedback inhibition?
Which of the following most accurately describes feedback inhibition? The end product of a metabolic pathway inhibits an earlier enzyme in the pathway.
Which is the difficult example of feedback inhibition?
Example: excess of glucose-6-phosphate stops the activity of enzyme hexokinase that helps in its formation from glucose and ATP.