What is the benefit of taking trimetazidine?
Trimetazidine helps to maintain the energy metabolism of heart muscle cells, protecting them from the effects of reduced oxygen supply. When you take this medication regularly on a long term basis, it can help treat angina by reducing the number of times you get angina.
What is the effect of trimetazidine?
Trimetazidine has a significant side effects profile, with the most common adverse reactions being nausea, vomiting, fatigue, dizziness, and myalgia. The drug can induce or increase parkinsonian symptoms: extrapyramidal rigidity, bradykinesia, and tremor.
What happens if you stop taking trimetazidine?
Do not stop taking your medication without checking with your healthcare professional. If you stop taking your medication, you may experience a worsening of your condition. This medicine should be taken with or after food.
What is brand name for trimetazidine?
Trimetazidine is marketed as Vastarel® in Denmark, France (Biopharma), Greece, Hong Kong, Ireland, Italy (Stroder), Portugal, Singapore and Thailand for the treatment of angina pectoris, vascular eye disorders and vestibular disorders such as vertigo and tinnitus associated with Ménière’s disease.
What should not be taken with trimetazidine?
Drug-Drug Interactions: TRIMETAZIDINE interacts with TRIMETAZIDINE, so it should be used with caution with sedatives or hypnotics (buspirone), strong painkillers, some allergy medications (chlorphenamine), certain antidepressants (fluoxetine and lithium), medicines to lower blood pressure (methyldopa), medicines to …
Is trimetazidine good for the heart?
Trimetazidine has been shown to enhance cardiac function by modulating cardiomyocyte autophagy. Indeed, administration of trimetazidine in diabetic cardiomyopathy rats was shown to enhance cardiomyocyte autophagy and improve cardiac function (Zhang et al., 2016).
Does trimetazidine give you energy?
Trimetazidine has been on the World Anti-Doping Agency’s list of banned substances since 2014. Unlike some other banned substances, trimetazidine does not give users an immediate boost in physical strength and energy.
Why would athletes use trimetazidine?
Trimetazidine is a metabolic agent that can help prevent angina attacks if used as an “add-on treatment,” according to the European Medicines Agency. It can increase blood flow efficiency and improve endurance — both crucial to any high-end athletic performance.
How long can you take trimetazidine?
Usually, TRIMETAZIDINE is prescribed for long-term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor’s consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.
What is trimetazidine and why is it banned?
The drug is currently listed as a “metabolic modulator” and WADA prohibits athletes from using the drug in or out of competition. A shift in how the body uses energy could give athletes an edge in competitions by lessening their altitude fatigue and increasing their cardiovascular fitness (Biomed. Pharmacother.