What is the drug Zonegran used for?

What is the drug Zonegran used for?

Zonisamide is used with other medications to prevent and control seizures (epilepsy). Zonisamide is a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor. It is unknown how zonisamide works to prevent seizures.

How long does Zonegran take to work?

It may take 2 weeks or longer before you feel the full benefit of zonisamide. Continue to take zonisamide even if you feel well. Do not stop taking zonisamide without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood.

Does Zonegran affect your memory?

The most common adverse reactions with ZONEGRAN (an incidence at least 4% greater than placebo) in controlled clinical trials and shown in descending order of frequency were somnolence, anorexia, dizziness, ataxia, agitation/irritability, and difficulty with memory and/or concentration.

Why do you take zonisamide at night?

Should zonisamide (Zonegran) be taken in the morning or at night? There is not a specific time of the day that you have to take zonisamide (Zonegran). However, it may be safer to take this medication in the evening time if you experience dizziness or sleepiness while on zonisamide (Zonegran).

Is Zonegran used for weight loss?

Zonegran is a medication we prescribe to help patients with weight loss. Originally, Zonegran was used as an anti-seizure medication. However, when doctors gave Zonegran to children for seizures, they stopped eating. Today, it is prescribed by itself or in combination with other medications for effective weight loss.

Is Zonegran a mood stabilizer?

Zonegran (zonisamide) is used with other medicines to help control partial seizures. It can’t be used by itself. Prevents seizures and stabilizes mood.

How much weight can you lose on Zonegran?

In the study, published last week in The Journal of the American Medical Association, a team led by Dr. Gadde found that Zonegran caused an average weight loss of about 20 pounds in obese people who took it for eight months. The loss approached 10 percent of body weight.

Does Zonegran Help Depression?

found that open label zonisamide (mean dose = 222.5 mg) given for 8 weeks to 20 patients with bipolar depression was associated with significant improvement in MADRS scores, although 10 patients terminated from the study due to side effects.

Has zonisamide been recalled 2022?

On April 25, 2022, Glenmark announced a consumer-level recall of several lots of zonisamide capsules due to gaps in the microbiology quality control system or due to lack of stability data. Zonisamide is indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy.

Why is zonisamide being discontinued?

Zonisamide discontinuation due to psychiatric and cognitive adverse events – PMC. The . gov means it’s official. Federal government websites often end in .

How fast do you lose weight on zonisamide?

The zonisamide group (n = 19) had a mean weight loss of 9.2 kg (1.7 kg) (9.4% loss) at week 32 compared with 1.5 kg (0.7 kg) (1.8% loss) for the placebo group (n = 17) (t = 4.0; P<. 001). Zonisamide was tolerated well, with few adverse effects.

Does Zonegran cause weight gain?

Longitudinal assessment indicated that zonisamide was associated with a significantly slower rate of BMI and weight increases compared with placebo (P = . 01). No patients in the zonisamide group experienced significant weight gain, compared with 33% of placebo-treated patients (P = . 009).

What are the long term side effects of zonisamide?

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Is zonisamide being discontinued?

ZONEGRAN (zonisamide) is indicated as adjunctive therapy in the treatment of partial seizures in adults with epilepsy. ZONEGRAN (zonisamide) capsules, 50 mg, is currently listed in the ”Discontinued Drug Product List” section of the Orange Book.