What causes atrophy of the optic nerve?

What causes atrophy of the optic nerve?

What causes optic nerve atrophy? ONA causes include: tumor, trauma, decreased blood supply (ischemia) or oxygen supply (hypoxia) causing swelling, hereditary, hydrocephalus, toxins, infection, and rare degenerative disorders. Onset can be from birth through adulthood.

What is atrophy of the eye?

Optic atrophy is a condition that affects the optic nerve, which carries impulses from the eye to the brain. (Atrophy means to waste away or deteriorate.) There is no effective treatment for this condition.

Is optic nerve atrophy progressive?

Dominant optic atrophy is inherited in an autosomal dominant fashion. It is believed to be the most common of the hereditary optic neuropathies, with prevalence in the range of 1:10,000 to 1:50,000. It is thought to be optic abiotrophy, premature degeneration of the optic nerve leading to progressive vision loss.

Can an optic nerve be repaired?

In the case of the optic nerve, it is a person’s vision that is lost or impaired. The optic nerve is part of the central nervous system and cannot regenerate or repair itself because of natural inhibitors in the body that block its re-growth.

What is Kjer’s optic atrophy?

Kjer’s optic neuropathy. Dominant optic atrophy, or dominant optic atrophy, Kjer’s type, is an autosomally inherited disease that affects the optic nerves, causing reduced visual acuity and blindness beginning in childhood. This condition is due to mitochondrial dysfunction mediating the death of optic nerve fibers.

What is optic atrophy?

Although dominant optic atrophy is the most common autosomally inherited optic neuropathy (i.e., disease of the optic nerves) aside from glaucoma, it is often misdiagnosed.

What is the clinical presentation of dominant optic atrophy (OA)?

Clinical presentation. Because the onset of Dominant optic atrophy is insidious, symptoms are often not noticed by the patients in its early stages and are picked up by chance in routine school eye screenings. First signs of Kjer’s typically present between 4–6 years of age, though presentation at as early as 1 year of age has been reported.

What are the signs and symptoms of bilateral optic atrophy?

This form of bilateral optic atrophy may have its onset in early childhood with optic disc pallor, loss of acuity, loss of color vision, and centrocecal scotomas. However, it is often not manifest until the second decade of life.

Related Post